When the woman begins to produce disturbances in the menstrual cycle and obesity - often accompanied by acne and increase the amount of hair or change in its distribution (hirsutism), it may be before the Polycystic Ovary Syndrome, PCOS The disease, also known as Stein-Leventhal syndrome, affects approximately 30% of women of childbearing age.
The S.O.P. is characterized by hormonal abnormalities that are at the same time cause and consequence of this disease.
According to the gynecologist and specialist in assisted reproduction, Selmo Geber, the constant state of amenorrhea (absence of menstruation) and oligomenorrhea (irregular cycle) due to anovulation, ultimately generating an endocrine disorder in the pattern. "Some patients have elevated levels of insulin - increasing the risk of diabetes - and they all have increased the production of androgen hormones: testosterone, androstenedione, DHEA and DHEA-S - that hinder the pregnancy," notes.
According to the doctor, the change in rates of insulin promotes damage not only in gynecology, but also is related to the incidence of obesity and high blood pressure. The anovulation, feature women who have the syndrome, is responsible for tables of infertility. But Sampaio explained that S.O.P. not interfere in the results of in vitro fertilization.
Geber out that treatment can be done with an emphasis in one of three goals, depending on which is predominant in each patient: the regularization of the menstrual cycle, the treatment of sterility or the improvement of hirsutism. "You should try to reduce the production and circulation of androgen hormones, and, where necessary, indicate the drugs that decrease peripheral insulin resistance," he says. "The goal is to protect the endometrium from the effects of constant exposure to estrogen, to prevent the effects of superinsulinemia for the body, induce ovulation to achieve and maintain pregnancy and support for control of ideal weight," he says. |