WITHDRAWAL OF CELLULAR FRAGMENTS IMPROVES IN PROCESS QUALITY EMBRYONNIC in vitro fertilization
A major focus in the area of reproductive medicine, today, is trying to better understand the mechanism of embryo implantation in the uterus, from the techniques of in vitro fertilization (IVF). With the full knowledge of the process of implantation, the pregnancy rates tend to increase even more.
One issue that must be considered when performing the in vitro fertilization, embryo is to check the quality. "The presence of cellular fragments in the embryo is an irregular cell division with involvement of the chance of implantation. Therefore, the tendency is to transfer embryos without fragments, trying to maintain the chances of pregnancy increased, "says the doctor Selmo Geber. Some situations can lead to formation of these fragments, such as the freezing of embryos and high maternal age. Sometimes, this fact is without any known cause. The biologist Renata embryology Bossi complements saying that the presence of these fragments is detrimental to the development: "This is because they contain free radicals, toxins that are extremely harmful to the embryo," he says.
A new alternative used by Origen Clinic to increase the chances of pregnancy is to remove the fragments before transferring them to the uterus. Was a hole in the zona pellucida (shell which is the embryo) using a laser specific for this type of procedure. Then, using a micropipette (the thickness of a strand of hair) to remove the fragment. The process must be done under microscopic vision and a micromanipulador. It is important to emphasize the need for extensive experience in micromanipulação and use of appropriate equipment for the process is not delayed in order not to jeopardize the embryonic development.
Thus, the embryos will have a better intercellular contact, improving the chance to have a proper development, and reduce the risk of degeneration. In summary, there is improvement in the quality of the embryo, increasing the chances of pregnancy.
Several pregnancies have been achieved through the removal of fragments of embryo fertilized in the laboratory. |